Dele Alli and Ryan Sessegnon remain unavailable for Saturday’s trip to Manchester City.
The pair are undertaking on-field rehabilitation as they work their way back from respective hamstring injuries.
They also sat out of last weekend’s opening-day victory at home to Aston Villa.
Heung-Min Son and Juan Foyth will also miss the fixture at the Etihad as they serve the final game of their three-match bans, picked up in the closing stages of last term.
Alongside this, defender Juan continues his rehabilitation from an ankle injury sustained in pre-season.
Kick-off at City on Saturday is at 5.30pm.